Proposed mechanisms for cancer- and treatment-related cognitive changes

John D. Merriman; Diane Von Ah; Christine Miaskowski; Bradley E. Aouizerat

doi:10.1016/j.soncn.2013.08.006

Proposed mechanisms for cancer- and treatment-related cognitive changes

John D. Merriman, Diane Von Ah, Christine Miaskowski, Bradley E. Aouizerat

Oral and Maxillofacial Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: To review the proposed mechanisms of cognitive changes associated with non-central nervous system cancers and cancer treatment. Data Sources: Review and synthesis of databased publications and review articles. Conclusion: Proposed mechanisms include cytokine upregulation, hormonal changes, neurotransmitter dysregulation, attentional fatigue, genetic predisposition, and comorbid symptoms. Implications for Nursing Practice: Oncology nurses need to understand the multiple mechanisms that may contribute to the development of cancer- and treatment-related cognitive changes so that they can identify patients at high risk and help patients understand why these changes occur.

Original language	English (US)
Pages (from-to)	260-269
Number of pages	10
Journal	Seminars in Oncology Nursing
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/j.soncn.2013.08.006
State	Published - Nov 2013

Keywords

Cancer
Cognition
Cytokines
Inflammation
Neurotransmitters

ASJC Scopus subject areas

Oncology(nursing)

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10.1016/j.soncn.2013.08.006

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title = "Proposed mechanisms for cancer- and treatment-related cognitive changes",

abstract = "Objectives: To review the proposed mechanisms of cognitive changes associated with non-central nervous system cancers and cancer treatment. Data Sources: Review and synthesis of databased publications and review articles. Conclusion: Proposed mechanisms include cytokine upregulation, hormonal changes, neurotransmitter dysregulation, attentional fatigue, genetic predisposition, and comorbid symptoms. Implications for Nursing Practice: Oncology nurses need to understand the multiple mechanisms that may contribute to the development of cancer- and treatment-related cognitive changes so that they can identify patients at high risk and help patients understand why these changes occur.",

keywords = "Cancer, Cognition, Cytokines, Inflammation, Neurotransmitters",

author = "Merriman, {John D.} and {Von Ah}, Diane and Christine Miaskowski and Aouizerat, {Bradley E.}",

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AU - Von Ah, Diane

AU - Miaskowski, Christine

AU - Aouizerat, Bradley E.

PY - 2013/11

Y1 - 2013/11

N2 - Objectives: To review the proposed mechanisms of cognitive changes associated with non-central nervous system cancers and cancer treatment. Data Sources: Review and synthesis of databased publications and review articles. Conclusion: Proposed mechanisms include cytokine upregulation, hormonal changes, neurotransmitter dysregulation, attentional fatigue, genetic predisposition, and comorbid symptoms. Implications for Nursing Practice: Oncology nurses need to understand the multiple mechanisms that may contribute to the development of cancer- and treatment-related cognitive changes so that they can identify patients at high risk and help patients understand why these changes occur.

AB - Objectives: To review the proposed mechanisms of cognitive changes associated with non-central nervous system cancers and cancer treatment. Data Sources: Review and synthesis of databased publications and review articles. Conclusion: Proposed mechanisms include cytokine upregulation, hormonal changes, neurotransmitter dysregulation, attentional fatigue, genetic predisposition, and comorbid symptoms. Implications for Nursing Practice: Oncology nurses need to understand the multiple mechanisms that may contribute to the development of cancer- and treatment-related cognitive changes so that they can identify patients at high risk and help patients understand why these changes occur.

KW - Cancer

KW - Cognition

KW - Cytokines

KW - Inflammation

KW - Neurotransmitters

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ER -

Proposed mechanisms for cancer- and treatment-related cognitive changes

Abstract

Keywords

ASJC Scopus subject areas

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