Prospects for gene-based immunopharmacology in salivary glands

Seiichi Yamano, Bruce J. Baum

Research output: Contribution to journalReview articlepeer-review


The clinical potential of gene transfer is increasing. One likely major application of this emerging biotechnology will be for gene therapeutics, the use of a gene as a drug. Salivary glands provide an unusual but increasingly valuable target site for gene transfer. Studies in animal salivary glands from several laboratories, including our own, have provided proof of this concept. In this review, we provide a background and perspective on possible strategies for gene-based immunopharmacology in salivary glands. We use as a target disease model the autoimmune exocrinopathy Sjogren's syndrome.

Original languageEnglish (US)
Pages (from-to)281-286
Number of pages6
JournalJapanese Journal of Pharmacology
Issue number4
StatePublished - 2000


  • Adeno-associated virus
  • Autoimmune disease
  • Cytokine
  • Gene therapeutics
  • Salivary gland

ASJC Scopus subject areas

  • Pharmacology


Dive into the research topics of 'Prospects for gene-based immunopharmacology in salivary glands'. Together they form a unique fingerprint.

Cite this