Prostate-specific Antigen Testing and Prostate Cancer Screening

Bob Djavan, Elisabeth Eckersberger, Julia Finkelstein, Helen Sadri, Samir S. Taneja, Herbert Lepor

    Research output: Contribution to journalReview article

    Abstract

    Prostate specific antigen (PSA) screening is an integral part of current screening for prostate cancer. Together with digital rectal examinations, it is recommended annually by the American Cancer Society. PSA screening has resulted in a significant stage migration in the past decades. Different forms of PSA, including free PSA, volume adjusted, complexed, intact, or pro-PSA, are being used in the screening process. Other aspects of the screening process include age at diagnosis, survival, overdiagnosis, and overtreatment. Recent studies have cast doubt on whether PSA screening positively affects mortality and how the quality of life of patients may be affected by screening. Future considerations include the need for more longitudinal studies as well as further study of the PSA components that may become more relevant in the future.

    Original languageEnglish (US)
    Pages (from-to)441-459
    Number of pages19
    JournalPrimary Care - Clinics in Office Practice
    Volume37
    Issue number3
    DOIs
    StatePublished - Sep 2010

    Keywords

    • Free PSA
    • PSA
    • Prostate Cancer
    • Screening

    ASJC Scopus subject areas

    • Pharmacology (medical)

    Fingerprint Dive into the research topics of 'Prostate-specific Antigen Testing and Prostate Cancer Screening'. Together they form a unique fingerprint.

    Cite this