Protein biomaterials for theranostic applications

Kamia Punia; Jacob B. Kronenberg; Jin Kim Montclare

doi:10.1039/c9me00143c

Protein biomaterials for theranostic applications

Kamia Punia, Jacob B. Kronenberg, Jin Kim Montclare

Chemical and Biomolecular Engineering

Research output: Contribution to journal › Review article › peer-review

Abstract

Protein biomaterials have been used for a wide range biomedical applications due to their intrinsic biocompatibility, versatility and higher order structure. Multifunctional theranostic agents fabricated by incorporating the diagnostic modalities and drug payloads in protein nanoformulations have garnered significant attention in recent years. Protein-based theranostic agents manifest high target specificity, enhanced blood circulation and reduce reticuloendothelial system elimination. This review focuses on the fabrication of peptide- and protein-based nanoformulations for imaging guided therapy.

Original language	English (US)
Pages (from-to)	1074-1094
Number of pages	21
Journal	Molecular Systems Design and Engineering
Volume	4
Issue number	6
DOIs	https://doi.org/10.1039/c9me00143c
State	Published - Dec 2019

ASJC Scopus subject areas

Chemistry (miscellaneous)
Chemical Engineering (miscellaneous)
Biomedical Engineering
Energy Engineering and Power Technology
Process Chemistry and Technology
Industrial and Manufacturing Engineering
Materials Chemistry

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10.1039/c9me00143c

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title = "Protein biomaterials for theranostic applications",

abstract = "Protein biomaterials have been used for a wide range biomedical applications due to their intrinsic biocompatibility, versatility and higher order structure. Multifunctional theranostic agents fabricated by incorporating the diagnostic modalities and drug payloads in protein nanoformulations have garnered significant attention in recent years. Protein-based theranostic agents manifest high target specificity, enhanced blood circulation and reduce reticuloendothelial system elimination. This review focuses on the fabrication of peptide- and protein-based nanoformulations for imaging guided therapy.",

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AU - Montclare, Jin Kim

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AB - Protein biomaterials have been used for a wide range biomedical applications due to their intrinsic biocompatibility, versatility and higher order structure. Multifunctional theranostic agents fabricated by incorporating the diagnostic modalities and drug payloads in protein nanoformulations have garnered significant attention in recent years. Protein-based theranostic agents manifest high target specificity, enhanced blood circulation and reduce reticuloendothelial system elimination. This review focuses on the fabrication of peptide- and protein-based nanoformulations for imaging guided therapy.

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Protein biomaterials for theranostic applications

Abstract

ASJC Scopus subject areas

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