Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold

Debarati M. Tagore; K. Ingrid Sprinz; Steven Fletcher; Janarthanan Jayawickramarajah; Andrew D. Hamilton

doi:10.1002/anie.200603479

Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold

Debarati M. Tagore, K. Ingrid Sprinz, Steven Fletcher, Janarthanan Jayawickramarajah, Andrew D. Hamilton

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Recognize this face? Quadruplex DNA has been used as a noncovalent scaffold to project binding groups for protein recognition and denaturation, with the best quadruplex decreasing the melting temperature of cytochrome c by about 45 K. (Figure Presented).

Original language	English (US)
Pages (from-to)	223-225
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	1-2
DOIs	https://doi.org/10.1002/anie.200603479
State	Published - 2007

Keywords

DNA structures
Enzymes
Self-assembly
Supramolecular chemistry
Surface recognition

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200603479

Cite this

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title = "Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold",

abstract = "Recognize this face? Quadruplex DNA has been used as a noncovalent scaffold to project binding groups for protein recognition and denaturation, with the best quadruplex decreasing the melting temperature of cytochrome c by about 45 K. (Figure Presented).",

keywords = "DNA structures, Enzymes, Self-assembly, Supramolecular chemistry, Surface recognition",

author = "Tagore, {Debarati M.} and Sprinz, {K. Ingrid} and Steven Fletcher and Janarthanan Jayawickramarajah and Hamilton, {Andrew D.}",

year = "2007",

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AU - Tagore, Debarati M.

AU - Sprinz, K. Ingrid

AU - Fletcher, Steven

AU - Jayawickramarajah, Janarthanan

AU - Hamilton, Andrew D.

PY - 2007

Y1 - 2007

N2 - Recognize this face? Quadruplex DNA has been used as a noncovalent scaffold to project binding groups for protein recognition and denaturation, with the best quadruplex decreasing the melting temperature of cytochrome c by about 45 K. (Figure Presented).

AB - Recognize this face? Quadruplex DNA has been used as a noncovalent scaffold to project binding groups for protein recognition and denaturation, with the best quadruplex decreasing the melting temperature of cytochrome c by about 45 K. (Figure Presented).

KW - DNA structures

KW - Enzymes

KW - Self-assembly

KW - Supramolecular chemistry

KW - Surface recognition

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Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold

Abstract

Keywords

ASJC Scopus subject areas

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