Proteinase-activated receptors: New functions for old enzymes

Stephan K. Böhm, Karen McConalogue, Wuyi Kong, Nigel W. Bunnett

Research output: Contribution to journalArticlepeer-review


Although proteases are traditionally viewed as degradative enzymes, characterization of a family of G protein-coupled receptors that are activated by proteolysis reveals a new role. Certain proteases function as signaling molecules that specifically regulate cells by cleaving and activating a family of proteinase-activated receptors.

Original languageEnglish (US)
Pages (from-to)231-240
Number of pages10
JournalNews in Physiological Sciences
Issue number5
StatePublished - Oct 1998

ASJC Scopus subject areas

  • Physiology


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