Pseudohexagonal 2D DNA crystals from double crossover cohesion

Baoquan Ding, Ruojie Sha, Nadrian C. Seeman

Research output: Contribution to journalArticlepeer-review


Two-dimensional pseudohexagonal trigonal arrays have been constructed by self-assembly from DNA. The motif used is a bulged-junction DNA triangle whose edges and extensions are DNA double crossover (DX) molecules, rather than conventional DNA double helices. Experiments were performed to establish whether the success of this system results from the added stiffness of DX molecules or the presence of two sticky ends at the terminus of each edge. Removal of one sticky end precludes lattice formation, suggesting that it is the double sticky end that is the primary factor enabling lattice formation.

Original languageEnglish (US)
Pages (from-to)10230-10231
Number of pages2
JournalJournal of the American Chemical Society
Issue number33
StatePublished - Aug 25 2004

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry
  • Biochemistry
  • Colloid and Surface Chemistry


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