Psychosocial Response to New-Onset Diabetes as a Long-Term Effect of Allogeneic Hematopoietic Stem Cell Transplantation

Jill M. Olausson, Lauren Clark, Janice M. Morse, Marilyn Hammer, Nancy Allen, Marcia Grant

Research output: Contribution to journalArticlepeer-review


Currently, little information is available to guide health care practitioners on how to facilitate positive outcomes in individuals who develop new-onset diabetes after allogeneic hematopoietic stem cell transplantation (allo HSCT) for treatment of hematological cancers. Results from this constructivist grounded theory study provide a theoretical framework explaining the psychosocial process of change that middle-age and older adults experience when developing new-onset diabetes in this context. Two predominant factors influenced this change: treatment burden and perception of diabetes. Key findings were that participants with ongoing complications, primarily graft-versus-host disease, experienced a high degree of treatment-related burden and unclear perceptions of diabetes when compared with those with no or few post-allo-HSCT complications. These factors limited their capacity to positively respond to and self-manage their condition. Implications for practice are to thoroughly consider these two factors when developing patient-centered interventions for middle-age and older adults with new-onset diabetes after allo HSCT.

Original languageEnglish (US)
Pages (from-to)1816-1827
Number of pages12
JournalQualitative Health Research
Issue number12
StatePublished - Oct 1 2017


  • United States
  • allogeneic hematopoietic stem cell transplantation
  • cancer
  • chronic illness and disease, experiences
  • diabetes
  • grounded theory, constructivist
  • middle age
  • older people
  • qualitative
  • research

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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