Quantitative analysis of ACE2 binding to coronavirus spike proteins: SARS-CoV-2vs.SARS-CoV and RaTG13

Medicine & Life Sciences

• Alanine 20%
• angiotensin converting enzyme 2 88%
• Chiroptera 12%
• Coronavirus 74%
• Coronavirus Spike Glycoproteins 100%
• Disease Outbreaks 8%
• Molecular Dynamics Simulation 10%
• Mutation 5%
• Protein Binding 9%
• Protein Domains 9%
• SARS Virus 87%
• Severe Acute Respiratory Syndrome 63%
• Thermodynamics 12%
• Viruses 6%

Physics & Astronomy

• affinity 28%
• alanine 16%
• angiotensins 99%
• bats 9%
• enzymes 63%
• free energy 5%
• interactions 2%
• molecular dynamics 4%
• mutations 7%
• proteins 47%
• quantitative analysis 59%
• scanning 8%
• simulation 5%
• spikes 59%
• thermodynamics 4%
• viruses 7%

Chemical Compounds

• Alanine 28%
• Gibbs Free Energy 11%
• Kd 44%
• Molecular Dynamics 10%
• Mutation 12%
• Protein 24%
• Thermodynamics 9%