Rapid and label-free optical discrimination of healthy and spiked urine samples

Muhammedin Deliorman; Roaa Alnemari; Mohammad A. Qasaimeh

Rapid and label-free optical discrimination of healthy and spiked urine samples

Muhammedin Deliorman, Roaa Alnemari, Mohammad A. Qasaimeh

Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The presence of prostate cancer cells in urine samples of cancer patients could be utilized as biomarker for early cancer detection. In this work, the UV absorption spectra of PC3 prostate cancer cells spiked in healthy urine were studied towards development of rapid, label-free, and non-invasive technology to optically detect their presence in patients' urine samples. A comparison of UV absorption spectra of PC3, MCF-7, and HeLa cells revealed that PC3 cells have distinctive peak characteristic at ∼204-206 nm with a wide shoulder in ∼260-290 nm region. Distinctive optical differences were also exhibited between PC3 cells and pelleted urinary cells.

Original language	English (US)
Title of host publication	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Publisher	Chemical and Biological Microsystems Society
Pages	2449-2450
Number of pages	2
ISBN (Electronic)	9781510897571
State	Published - Jan 1 2018
Event	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China Duration: Nov 11 2018 → Nov 15 2018

Publication series

Name	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume	4

Conference

Conference	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Country/Territory	Taiwan, Province of China
City	Kaohsiung
Period	11/11/18 → 11/15/18

Keywords

Cancer detection
Optical absorption
Prostate cancer cells
Ultraviolet fluorescence
Urine

ASJC Scopus subject areas

General Chemistry
Bioengineering
Chemical Engineering (miscellaneous)
Control and Systems Engineering

Cite this

Deliorman, M., Alnemari, R., & Qasaimeh, M. A. (2018). Rapid and label-free optical discrimination of healthy and spiked urine samples. In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 (pp. 2449-2450). (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; Vol. 4). Chemical and Biological Microsystems Society.

Rapid and label-free optical discrimination of healthy and spiked urine samples. / Deliorman, Muhammedin; Alnemari, Roaa; Qasaimeh, Mohammad A.
22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, 2018. p. 2449-2450 (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; Vol. 4).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Deliorman, M, Alnemari, R & Qasaimeh, MA 2018, Rapid and label-free optical discrimination of healthy and spiked urine samples. in 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, vol. 4, Chemical and Biological Microsystems Society, pp. 2449-2450, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, Kaohsiung, Taiwan, Province of China, 11/11/18.

Deliorman M, Alnemari R, Qasaimeh MA. Rapid and label-free optical discrimination of healthy and spiked urine samples. In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society. 2018. p. 2449-2450. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018).

Deliorman, Muhammedin ; Alnemari, Roaa ; Qasaimeh, Mohammad A. / Rapid and label-free optical discrimination of healthy and spiked urine samples. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, 2018. pp. 2449-2450 (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018).

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Rapid and label-free optical discrimination of healthy and spiked urine samples

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

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Cite this