Rapid non-invasive tests for diagnostics of infectious diseases

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A rapid test for an infectious disease that can be used at point-of-care at a physician's office, a pharmacy, or in the field is critical for the prompt and appropriate therapeutic intervention. Ultimately by treating infections early on will decrease transmission of the pathogen. In contrast to metabolic diseases or cancer where multiple biomarkers are required, infectious disease targets (e.g. antigen, antibody, nucleic acid) are simple and specific for the pathogen causing the disease. Our laboratory has focused on three major infectious disease; HIV, Tuberculosis, and Malaria. These diseases are pandemic in much of the world thus putting natives, tourists and military personnel at risk for becoming infected, and upon returning to the U.S., transmitting these diseases to their contacts. Our devices are designed to detect antigens, antibodies or nucleic acids in blood or saliva samples in less than 30 minutes. An overview describing the current status of each of the three diagnostic platforms is presented. These microfluidic point-of-care devices will be relatively inexpensive, disposable, and user friendly.

Original languageEnglish (US)
Title of host publicationSensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV
PublisherSPIE
ISBN (Print)9781628410495
DOIs
StatePublished - 2014
EventSensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV - Baltimore, MD, United States
Duration: May 5 2014May 7 2014

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9112
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Other

OtherSensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV
CountryUnited States
CityBaltimore, MD
Period5/5/145/7/14

Keywords

  • HIV
  • Malaria
  • Point-of-care
  • TB

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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