Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes

Edwina C. Lerner, Yimin Qian, Michelle A. Blaskovich, Renae D. Fossum, Andreas Vogt, Jiazhi Sun, Adrienne D. Cox, Channing J. Der, Andrew D. Hamilton, Saïd M. Sebti

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Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience

Biochemistry, Genetics and Molecular Biology