Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector

Zeta T.F. Yu; Nam T. Vu; Ken Ichiro Kamei; Canny Y.N. Chang; Robert W. Silverman; Richard Farrell; Kanai S. Shah; Michael E. Phelps; Caius G. Radu; Arion F. Chatziioannou; Hsian Rong Tseng

Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector

Zeta T.F. Yu, Nam T. Vu, Ken Ichiro Kamei, Canny Y.N. Chang, Robert W. Silverman, Richard Farrell, Kanai S. Shah, Michael E. Phelps, Caius G. Radu, Arion F. Chatziioannou, Hsian Rong Tseng

Biology

Research output: Contribution to conference › Paper › peer-review

Abstract

We present a systematic study of a novel microfluidic platform capable of in situ detection of [¹⁸F]2-fluoro-2-deoxy-D-glucose ([ ¹⁸F]FDG), a glucose analog, in living cell(s), which is unprecedented using conventional technology. We investigated various operation parameters (e.g., [¹⁸F]FDG concentration and cell types) by performing sensitive detection of [18F]FDG utilization in a small number of cells (i.e., 1-100 cells).

Original language	English (US)
Pages	573-575
Number of pages	3
State	Published - 2008
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: Oct 12 2008 → Oct 16 2008

Other

Other	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	10/12/08 → 10/16/08

Keywords

Cell culture
FDG uptake
Glucose utilization
PSAPD

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

Yu, Z. T. F., Vu, N. T., Kamei, K. I., Chang, C. Y. N., Silverman, R. W., Farrell, R., Shah, K. S., Phelps, M. E., Radu, C. G., Chatziioannou, A. F., & Tseng, H. R. (2008). Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector. 573-575. Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector. / Yu, Zeta T.F.; Vu, Nam T.; Kamei, Ken Ichiro et al.
2008. 573-575 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conference › Paper › peer-review

Yu, ZTF, Vu, NT, Kamei, KI, Chang, CYN, Silverman, RW, Farrell, R, Shah, KS, Phelps, ME, Radu, CG, Chatziioannou, AF & Tseng, HR 2008, 'Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector', Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States, 10/12/08 - 10/16/08 pp. 573-575.

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title = "Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector",

abstract = "We present a systematic study of a novel microfluidic platform capable of in situ detection of [18F]2-fluoro-2-deoxy-D-glucose ([ 18F]FDG), a glucose analog, in living cell(s), which is unprecedented using conventional technology. We investigated various operation parameters (e.g., [18F]FDG concentration and cell types) by performing sensitive detection of [18F]FDG utilization in a small number of cells (i.e., 1-100 cells).",

keywords = "Cell culture, FDG uptake, Glucose utilization, PSAPD",

author = "Yu, {Zeta T.F.} and Vu, {Nam T.} and Kamei, {Ken Ichiro} and Chang, {Canny Y.N.} and Silverman, {Robert W.} and Richard Farrell and Shah, {Kanai S.} and Phelps, {Michael E.} and Radu, {Caius G.} and Chatziioannou, {Arion F.} and Tseng, {Hsian Rong}",

year = "2008",

language = "English (US)",

pages = "573--575",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

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TY - CONF

T1 - Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector

AU - Yu, Zeta T.F.

AU - Vu, Nam T.

AU - Kamei, Ken Ichiro

AU - Chang, Canny Y.N.

AU - Silverman, Robert W.

AU - Farrell, Richard

AU - Shah, Kanai S.

AU - Phelps, Michael E.

AU - Radu, Caius G.

AU - Chatziioannou, Arion F.

AU - Tseng, Hsian Rong

PY - 2008

Y1 - 2008

N2 - We present a systematic study of a novel microfluidic platform capable of in situ detection of [18F]2-fluoro-2-deoxy-D-glucose ([ 18F]FDG), a glucose analog, in living cell(s), which is unprecedented using conventional technology. We investigated various operation parameters (e.g., [18F]FDG concentration and cell types) by performing sensitive detection of [18F]FDG utilization in a small number of cells (i.e., 1-100 cells).

AB - We present a systematic study of a novel microfluidic platform capable of in situ detection of [18F]2-fluoro-2-deoxy-D-glucose ([ 18F]FDG), a glucose analog, in living cell(s), which is unprecedented using conventional technology. We investigated various operation parameters (e.g., [18F]FDG concentration and cell types) by performing sensitive detection of [18F]FDG utilization in a small number of cells (i.e., 1-100 cells).

KW - Cell culture

KW - FDG uptake

KW - Glucose utilization

KW - PSAPD

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M3 - Paper

AN - SCOPUS:84902505285

SP - 573

EP - 575

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Real-time monitoring glucose utilization in single cell using a cell culture chip with an embedded detector

Abstract

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Keywords

ASJC Scopus subject areas

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