Recent developments in the identification of chemotherapeutics for Chagas Disease

Jeffrey W. Lockman; Andrew D. Hamilton

doi:10.2174/0929867053507289

Recent developments in the identification of chemotherapeutics for Chagas Disease

Jeffrey W. Lockman, Andrew D. Hamilton

Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

Chagas Disease, caused by the T. cruzi parasite, is one of the largest public health problems in the Western hemisphere. Although its spread has diminished due to vector eradication programs, effective chemotherapeutics for the disease itself remain elusive. Many efforts towards the development of antiparasitic agents active against a number of targets have been described recently in the literature. This review summarizes developments in trypanosidal agents from 2000 through 2003.

Original language	English (US)
Pages (from-to)	945-959
Number of pages	15
Journal	Current Medicinal Chemistry
Volume	12
Issue number	8
DOIs	https://doi.org/10.2174/0929867053507289
State	Published - 2005

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Pharmacology
Drug Discovery
Organic Chemistry

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abstract = "Chagas Disease, caused by the T. cruzi parasite, is one of the largest public health problems in the Western hemisphere. Although its spread has diminished due to vector eradication programs, effective chemotherapeutics for the disease itself remain elusive. Many efforts towards the development of antiparasitic agents active against a number of targets have been described recently in the literature. This review summarizes developments in trypanosidal agents from 2000 through 2003.",

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Recent developments in the identification of chemotherapeutics for Chagas Disease

Abstract

ASJC Scopus subject areas

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