TY - JOUR
T1 - Recovery of the fetal electrocardiogram for morphological analysis from two trans-abdominal channels via optimal shrinkage
AU - Su, Pei Chun
AU - Miller, Stephen
AU - Idriss, Salim
AU - Barker, Piers
AU - Wu, Hau Tieng
N1 - Publisher Copyright:
© 2019 Institute of Physics and Engineering in Medicine.
PY - 2019/12/2
Y1 - 2019/12/2
N2 - Objective : We propose a novel algorithm to recover fetal electrocardiogram (ECG) for both the fetal heart rate analysis and morphological analysis of its waveform from two or three trans-abdominal maternal ECG channels. Approach: We design an algorithm based on the optimal-shrinkage under the wave-shape manifold model. For the fetal heart rate analysis, the algorithm is evaluated on publicly available database, 2013 PhyioNet/Computing in Cardiology Challenge, set A (CinC2013). For the morphological analysis, we analyze CinC2013 and another publicly available database, non-invasive fetal ECG arrhythmia database (nifeadb), and propose to simulate semi-real databases by mixing the MIT-BIH normal sinus rhythm database and MITDB arrhythmia database. Main results: For the fetal R peak detection, the proposed algorithm outperforms all algorithms under comparison. For the morphological analysis, the algorithm provides an encouraging result in recovery of the fetal ECG waveform, including PR, QT and ST intervals, even when the fetus has arrhythmia, both in real and simulated databases. Significance: To the best of our knowledge, this is the first work focusing on recovering the fetal ECG for morphological analysis from two or three channels with an algorithm potentially applicable for continuous fetal electrocardiographic monitoring, which creates the potential for long term monitoring purpose.
AB - Objective : We propose a novel algorithm to recover fetal electrocardiogram (ECG) for both the fetal heart rate analysis and morphological analysis of its waveform from two or three trans-abdominal maternal ECG channels. Approach: We design an algorithm based on the optimal-shrinkage under the wave-shape manifold model. For the fetal heart rate analysis, the algorithm is evaluated on publicly available database, 2013 PhyioNet/Computing in Cardiology Challenge, set A (CinC2013). For the morphological analysis, we analyze CinC2013 and another publicly available database, non-invasive fetal ECG arrhythmia database (nifeadb), and propose to simulate semi-real databases by mixing the MIT-BIH normal sinus rhythm database and MITDB arrhythmia database. Main results: For the fetal R peak detection, the proposed algorithm outperforms all algorithms under comparison. For the morphological analysis, the algorithm provides an encouraging result in recovery of the fetal ECG waveform, including PR, QT and ST intervals, even when the fetus has arrhythmia, both in real and simulated databases. Significance: To the best of our knowledge, this is the first work focusing on recovering the fetal ECG for morphological analysis from two or three channels with an algorithm potentially applicable for continuous fetal electrocardiographic monitoring, which creates the potential for long term monitoring purpose.
KW - fetal ECG morphology
KW - noninvasive fetal ECG
KW - optimal shrinkage
KW - wave-shape manifold
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U2 - 10.1088/1361-6579/ab4b13
DO - 10.1088/1361-6579/ab4b13
M3 - Article
C2 - 31585453
AN - SCOPUS:85075963421
SN - 0967-3334
VL - 40
JO - Physiological Measurement
JF - Physiological Measurement
IS - 11
M1 - 115005
ER -