TY - JOUR
T1 - Reduced field-of-view diffusion-weighted magnetic resonance imaging of the prostate at 3 tesla
T2 - Comparison with standard echo-planar imaging technique for image quality and tumor assessment
AU - Tamada, Tsutomu
AU - Ream, Justin M.
AU - Doshi, Ankur M.
AU - Taneja, Samir S.
AU - Rosenkrantz, Andrew B.
PY - 2017
Y1 - 2017
N2 - Objective: The purpose of this study was to compare image quality and tumor assessment at prostate magnetic resonance imaging (MRI) between reduced field-of-view diffusion-weighted imaging (rFOV-DWI) and standard DWI (st-DWI). Methods: Atotal of 49 patients undergoing prostateMRI and MRI/ultrasound fusion-targeted biopsy were included. Examinations included st-DWI (field of view [FOV], 200 × 200 mm) and rFOV-DWI (FOV, 140 × 64 mm) using a 2-dimensional (2D) spatially-selective radiofrequency pulse and parallel transmission. Two readers performed qualitative assessments; a third reader performed quantitative evaluation. Results: Overall image quality, anatomic distortion, visualization of capsule, and visualization of peripheral/transition zone edge were better for rFOV-DWI for reader 1 (P ≤ 0.002), although not for reader 2 (P ≥ 0.567). For both readers, sensitivity, specificity, and accuracy for tumor with a Gleason Score (GS) of 3 + 4 or higher were not different (P ≥ 0.289). Lesion clarity was higher for st-DWI for reader 2 (P = 0.008), although similar for reader 1 (P = 0.409). Diagnostic confidence was not different for either reader (P ≥ 0.052). Tumor-to-benign apparent diffusion coefficient ratio was not different (P = 0.675). Conclusions: Potentially improved image quality of rFOV-DWI did not yield improved tumor assessment. Continued optimization is warranted.
AB - Objective: The purpose of this study was to compare image quality and tumor assessment at prostate magnetic resonance imaging (MRI) between reduced field-of-view diffusion-weighted imaging (rFOV-DWI) and standard DWI (st-DWI). Methods: Atotal of 49 patients undergoing prostateMRI and MRI/ultrasound fusion-targeted biopsy were included. Examinations included st-DWI (field of view [FOV], 200 × 200 mm) and rFOV-DWI (FOV, 140 × 64 mm) using a 2-dimensional (2D) spatially-selective radiofrequency pulse and parallel transmission. Two readers performed qualitative assessments; a third reader performed quantitative evaluation. Results: Overall image quality, anatomic distortion, visualization of capsule, and visualization of peripheral/transition zone edge were better for rFOV-DWI for reader 1 (P ≤ 0.002), although not for reader 2 (P ≥ 0.567). For both readers, sensitivity, specificity, and accuracy for tumor with a Gleason Score (GS) of 3 + 4 or higher were not different (P ≥ 0.289). Lesion clarity was higher for st-DWI for reader 2 (P = 0.008), although similar for reader 1 (P = 0.409). Diagnostic confidence was not different for either reader (P ≥ 0.052). Tumor-to-benign apparent diffusion coefficient ratio was not different (P = 0.675). Conclusions: Potentially improved image quality of rFOV-DWI did not yield improved tumor assessment. Continued optimization is warranted.
KW - 3 T
KW - DWI
KW - MRI
KW - Prostate biopsy
KW - Prostatic cancer
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U2 - 10.1097/RCT.0000000000000634
DO - 10.1097/RCT.0000000000000634
M3 - Article
C2 - 28806322
AN - SCOPUS:85038130056
VL - 41
SP - 949
EP - 956
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
SN - 0363-8715
IS - 6
ER -