Reversible molecular adsorption based on multiple-point interaction by shrinkable gels

Taro Oya; Takashi Enoki; Alexander Yu Grosberg; Satoru Masamune; Takaharu Sakiyama; Yukikazu Takeoka; Kazunori Tanaka; Guoqiang Wang; Yasar Yilmaz; Michael S. Feld; Ramachandra Dasari; Toyoichi Tanaka

doi:10.1126/science.286.5444.1543

Reversible molecular adsorption based on multiple-point interaction by shrinkable gels

Taro Oya, Takashi Enoki, Alexander Yu Grosberg, Satoru Masamune, Takaharu Sakiyama, Yukikazu Takeoka, Kazunori Tanaka, Guoqiang Wang, Yasar Yilmaz, Michael S. Feld, Ramachandra Dasari, Toyoichi Tanaka

Research output: Contribution to journal › Article › peer-review

Abstract

A general approach is presented for creating polymer gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule. Multiple-point interaction is experimentally proven by power laws found between the affinity and the concentration of the adsorbing monomers within the gels.

Original language	English (US)
Pages (from-to)	1543-1545
Number of pages	3
Journal	Science
Volume	286
Issue number	5444
DOIs	https://doi.org/10.1126/science.286.5444.1543
State	Published - Nov 19 1999

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title = "Reversible molecular adsorption based on multiple-point interaction by shrinkable gels",

abstract = "A general approach is presented for creating polymer gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule. Multiple-point interaction is experimentally proven by power laws found between the affinity and the concentration of the adsorbing monomers within the gels.",

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year = "1999",

month = nov,

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doi = "10.1126/science.286.5444.1543",

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T1 - Reversible molecular adsorption based on multiple-point interaction by shrinkable gels

AU - Oya, Taro

AU - Enoki, Takashi

AU - Grosberg, Alexander Yu

AU - Masamune, Satoru

AU - Sakiyama, Takaharu

AU - Takeoka, Yukikazu

AU - Tanaka, Kazunori

AU - Wang, Guoqiang

AU - Yilmaz, Yasar

AU - Feld, Michael S.

AU - Dasari, Ramachandra

AU - Tanaka, Toyoichi

PY - 1999/11/19

Y1 - 1999/11/19

N2 - A general approach is presented for creating polymer gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule. Multiple-point interaction is experimentally proven by power laws found between the affinity and the concentration of the adsorbing monomers within the gels.

AB - A general approach is presented for creating polymer gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule. Multiple-point interaction is experimentally proven by power laws found between the affinity and the concentration of the adsorbing monomers within the gels.

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Reversible molecular adsorption based on multiple-point interaction by shrinkable gels

Abstract

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