Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors

Matthew Volgraf, Pau Gorostiza, Stephanie Szobota, Max R. Helix, Ehud Y. Isacoff, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

The design, synthesis, and biological evaluation of a photochromic glutamate analogue is described. The molecule functions as a reversibly caged neurotransmitter and can be used to influence neural activity with light.

Original languageEnglish (US)
Pages (from-to)260-261
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number2
DOIs
StatePublished - Jan 17 2007

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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