Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors

Matthew Volgraf; Pau Gorostiza; Stephanie Szobota; Max R. Helix; Ehud Y. Isacoff; Dirk Trauner

doi:10.1021/ja067269o

Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors

Matthew Volgraf, Pau Gorostiza, Stephanie Szobota, Max R. Helix, Ehud Y. Isacoff, Dirk Trauner

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The design, synthesis, and biological evaluation of a photochromic glutamate analogue is described. The molecule functions as a reversibly caged neurotransmitter and can be used to influence neural activity with light.

Original language	English (US)
Pages (from-to)	260-261
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	129
Issue number	2
DOIs	https://doi.org/10.1021/ja067269o
State	Published - Jan 17 2007

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja067269o

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abstract = "The design, synthesis, and biological evaluation of a photochromic glutamate analogue is described. The molecule functions as a reversibly caged neurotransmitter and can be used to influence neural activity with light.",

author = "Matthew Volgraf and Pau Gorostiza and Stephanie Szobota and Helix, {Max R.} and Isacoff, {Ehud Y.} and Dirk Trauner",

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AU - Trauner, Dirk

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Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors

Abstract

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