Risk of preterm and early term birth by maternal drug use

Rebecca J. Baer, Christina D. Chambers, Kelli K. Ryckman, Scott P. Oltman, Larry Rand, Laura L. Jelliffe-Pawlowski

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Examine the risk of preterm birth (PTB, < 37 weeks) and early term birth (37–38 weeks) for women with reported drug abuse/dependence. Study Design: The population was drawn from singleton livebirths in California from 2007 to 2012. Drug abuse/dependence was determined from maternal diagnostic codes (opioid, cocaine, cannabis, amphetamine, other, or polysubstance). Relative risks, adjusted for maternal factors were calculated for PTB and early term birth. Result: Of the 2,890,555 women in the sample, 1.7% (n = 48,133) had a diagnostic code for drug abuse/dependence. The percentage of PTBs varied from 11.6% (cannabis) to 24.3% (cocaine), compared with 6.7% of women without reported drug abuse/dependence. Conclusion: Women with reported drug abuse/dependence during pregnancy were at increased risk of having a PTB and all but those using cannabis were at risk of having an early term birth. Women using cocaine and polysubstance were at the highest risk of birth < 32 weeks.

Original languageEnglish (US)
Pages (from-to)286-294
Number of pages9
JournalJournal of Perinatology
Volume39
Issue number2
DOIs
StatePublished - Feb 1 2019

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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