Role of transposable elements in trypanosomatids

Frédéric Bringaud; Elodie Ghedin; Najib M A El-Sayed; Barbara Papadopoulou

doi:10.1016/j.micinf.2008.02.009

Role of transposable elements in trypanosomatids

Frédéric Bringaud, Elodie Ghedin, Najib M A El-Sayed, Barbara Papadopoulou

Research output: Contribution to journal › Short survey › peer-review

Abstract

Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.

Original language	English (US)
Pages (from-to)	575-581
Number of pages	7
Journal	Microbes and Infection
Volume	10
Issue number	6
DOIs	https://doi.org/10.1016/j.micinf.2008.02.009
State	Published - May 2008

Keywords

Cellular function
Domestication
Evolution
Gene expression
Leishmania
Regulation of mRNA stability
Retroposon
Transposable element
Trypanosoma

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

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10.1016/j.micinf.2008.02.009

Cite this

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title = "Role of transposable elements in trypanosomatids",

abstract = "Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.",

keywords = "Cellular function, Domestication, Evolution, Gene expression, Leishmania, Regulation of mRNA stability, Retroposon, Transposable element, Trypanosoma",

author = "Fr{\'e}d{\'e}ric Bringaud and Elodie Ghedin and El-Sayed, {Najib M A} and Barbara Papadopoulou",

note = "Funding Information: The authors are extremely grateful to the sequencing teams involved in the TriTryp genomes sequencing projects (TIGR, the Wellcome Trust Sanger Institute, the SBRI and the Karolinska Institute Center for Genomics and Bioinformatics) for the chromosome sequences accessible on the Trypanosomatid genome database ( http://www.genedb.org/genedb/ ). Fr{\'e}d{\'e}ric Bringaud is supported by the CNRS and the Universit{\'e} Victor Segalen Bordeaux 2.",

year = "2008",

month = may,

doi = "10.1016/j.micinf.2008.02.009",

language = "English (US)",

volume = "10",

pages = "575--581",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson s.r.l.",

number = "6",

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TY - JOUR

T1 - Role of transposable elements in trypanosomatids

AU - Bringaud, Frédéric

AU - Ghedin, Elodie

AU - El-Sayed, Najib M A

AU - Papadopoulou, Barbara

N1 - Funding Information: The authors are extremely grateful to the sequencing teams involved in the TriTryp genomes sequencing projects (TIGR, the Wellcome Trust Sanger Institute, the SBRI and the Karolinska Institute Center for Genomics and Bioinformatics) for the chromosome sequences accessible on the Trypanosomatid genome database ( http://www.genedb.org/genedb/ ). Frédéric Bringaud is supported by the CNRS and the Université Victor Segalen Bordeaux 2.

PY - 2008/5

Y1 - 2008/5

N2 - Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.

AB - Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.

KW - Cellular function

KW - Domestication

KW - Evolution

KW - Gene expression

KW - Leishmania

KW - Regulation of mRNA stability

KW - Retroposon

KW - Transposable element

KW - Trypanosoma

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U2 - 10.1016/j.micinf.2008.02.009

DO - 10.1016/j.micinf.2008.02.009

M3 - Short survey

C2 - 18467144

AN - SCOPUS:44449128473

SN - 1286-4579

VL - 10

SP - 575

EP - 581

JO - Microbes and Infection

JF - Microbes and Infection

IS - 6

ER -

Role of transposable elements in trypanosomatids

Abstract

Keywords

ASJC Scopus subject areas

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