Saccade planning evokes topographically specific activity in the dorsal and ventral streams

Golbarg T. Saber, Franco Pestilli, Clayton E. Curtis

Research output: Contribution to journalArticle

Abstract

Saccade planning may invoke spatially-specific feedback signals that bias early visual activity in favor of top-down goals. We tested this hypothesis by measuring cortical activity at the early stages of the dorsal and ventral visual processing streams. Human subjects maintained saccade plans to (prosaccade) or away (antisaccade) from a spatial location over long memory-delays. Results show that cortical activity persists in early visual cortex at the retinotopic location of upcoming saccade goals. Topographically specific activity persists as early as V1, and activity increases along both dorsal (V3A/B, IPS0) and ventral (hV4, VO1) visual areas. Importantly, activity persists when saccade goals are available only via working memory and when visual targets and saccade goals are spatially disassociated. We conclude that top-down signals elicit retinotopically specific activity in visual cortex both in the dorsal and ventral streams. Such activity may underlie mechanisms that prioritize locations of task-relevant objects.

Original languageEnglish (US)
Pages (from-to)245-252
Number of pages8
JournalJournal of Neuroscience
Volume35
Issue number1
DOIs
StatePublished - Jan 7 2015

Keywords

  • Antisaccade
  • FMRI
  • Retinotopy
  • Saccade
  • Spatial cognition
  • Working memory

ASJC Scopus subject areas

  • Neuroscience(all)

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