Salivary glands as a model for craniofacial applications of gene transfer

Bruce J. Baum, Corinne M. Goldsmith, A. T.M.Shamsul Hoque, Robert B. Wellner, Lorena Baccaglini, Chuantian Ding, Seiichi Yamano, Changyu Zheng, Doron J. Aframian, Brian C. O'Connell

Research output: Contribution to journalReview articlepeer-review


The potential applications of gene transfer technology to all branches of medicine are increasing. It is quite likely that within the next 10-20 years surgical practice routinely will utilize gene transfer, at least adjunctively. The purpose of this review is to familiarize the oral and maxillofacial surgeon with this technology. Studies performed with salivary glands in animal models are presented as examples of proof of concept.

Original languageEnglish (US)
Pages (from-to)163-166
Number of pages4
JournalInternational Journal of Oral and Maxillofacial Surgery
Issue number3
StatePublished - Jun 2000


  • Gene therapeutics
  • Gene therapy
  • Molecular medicine
  • Salivary glands

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology


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