Scale-invariant spatial patterns in genome organization

Michael D. Purugganan

doi:10.1016/0375-9601(93)90836-O

Scale-invariant spatial patterns in genome organization

Research output: Contribution to journal › Article › peer-review

Abstract

Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.

Original language	English (US)
Pages (from-to)	252-256
Number of pages	5
Journal	Physics Letters A
Volume	175
Issue number	3-4
DOIs	https://doi.org/10.1016/0375-9601(93)90836-O
State	Published - Apr 12 1993

ASJC Scopus subject areas

General Physics and Astronomy

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10.1016/0375-9601(93)90836-O

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abstract = "Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.",

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AB - Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.

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Scale-invariant spatial patterns in genome organization

Abstract

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