TY - JOUR
T1 - Scale-invariant spatial patterns in genome organization
AU - Purugganan, Michael D.
PY - 1993/4/12
Y1 - 1993/4/12
N2 - Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.
AB - Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.
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U2 - 10.1016/0375-9601(93)90836-O
DO - 10.1016/0375-9601(93)90836-O
M3 - Article
AN - SCOPUS:24644515199
SN - 0375-9601
VL - 175
SP - 252
EP - 256
JO - Physics Letters, Section A: General, Atomic and Solid State Physics
JF - Physics Letters, Section A: General, Atomic and Solid State Physics
IS - 3-4
ER -