Securing digital microfluidic biochips by randomizing checkpoints

Jack Tang, Ramesh Karri, Mohamed Ibrahim, Krishnendu Chakrabarty

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Much progress has been made in digital microfluidic biochips (DMFB), with a great body of literature addressing low-cost, high-performance, and reliable operation. Despite this progress, security of DMFBs has not been adequately addressed. We present an analysis of a DMFB system prone to malicious modification of routes and propose a DMFB defense based on spatio-Temporal randomized checkpoints using CCD cameras. Absent the knowledge of the time-and space-randomized checkpoints, an attacker cannot navigate the DMFB without alerting the system. We present an algorithm to guide the placement and timing of the checkpoints such that the probability that an attack can evade detection is minimized. The efficacy of the defense mechanism is illustrated with a case study under stealthy malicious modifications.

Original languageEnglish (US)
Title of host publicationProceedings - 2016 IEEE International Test Conference, ITC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467387736
StatePublished - Jul 2 2016
Event47th IEEE International Test Conference, ITC 2016 - Fort Worth, United States
Duration: Nov 15 2016Nov 17 2016

Publication series

NameProceedings - International Test Conference
ISSN (Print)1089-3539


Other47th IEEE International Test Conference, ITC 2016
Country/TerritoryUnited States
CityFort Worth

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Applied Mathematics


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