Security implications of cyberphysical flow-based microfluidic biochips

Jack Tang, Mohamed Ibrahim, Krishnendu Chakrabarty, Ramesh Karri

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Flow-based microfluidic biochips are revolutionizing biochemical research by automating complex protocols and reducing sample and reagent consumption. Integration of these biochips with sensors, actuators, and intelligent control have compounded these benefits while increasing reliability. And, many flow-based platforms have successfully transitioned to the marketplace, demonstrating their utility through several recent scientific publications. However, these microfluidic technologies and platforms have unintended security and trust implications that threaten their continued success. We survey cyberphysical flow-based microfluidic platforms and perform a security assessment. We then describe an attack on digital polymerase chain reactions and how such attacks undermine research integrity.

Original languageEnglish (US)
Title of host publicationProceedings - 2017 IEEE 26th Asian Test Symposium, ATS 2017
PublisherIEEE Computer Society
Number of pages6
ISBN (Electronic)9781538624364
StatePublished - Jan 24 2018
Event26th IEEE Asian Test Symposium, ATS 2017 - Taipei, Taiwan, Province of China
Duration: Nov 27 2017Nov 30 2017

Publication series

NameProceedings of the Asian Test Symposium
ISSN (Print)1081-7735


Other26th IEEE Asian Test Symposium, ATS 2017
Country/TerritoryTaiwan, Province of China


  • Biochips
  • Cyberphysical systems
  • Microfluidics
  • Security
  • Trust

ASJC Scopus subject areas

  • Electrical and Electronic Engineering


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