Selecting ordered environments in NMR of spin 3/2 nuclei via frequency-sweep pulses

Wen Ling; Alexej Jerschow

doi:10.1016/j.jmr.2005.06.006

Selecting ordered environments in NMR of spin 3/2 nuclei via frequency-sweep pulses

Wen Ling, Alexej Jerschow

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We demonstrate that frequency-swept pulses can be used for the selective and enhanced detection of quadrupolar nuclei located in anisotropic environments. The primary driving force for this technique development is the field of sodium-MRI, where sodium signals from locally ordered environments are known to be diagnostic of cartilage defects. We demonstrate here simple one-dimensional images of model systems, in which the signals from free sodium ions are suppressed, while ordered sodium is detected via the narrow central transition signal.

Original language	English (US)
Pages (from-to)	234-238
Number of pages	5
Journal	Journal of Magnetic Resonance
Volume	176
Issue number	2
DOIs	https://doi.org/10.1016/j.jmr.2005.06.006
State	Published - Oct 2005

Keywords

Contrast mechanism
Double-frequency sweep
Double-quantum filter
Quadrupolar coupling
Satellite transitions
Sodium MRI

ASJC Scopus subject areas

Biophysics
Biochemistry
Nuclear and High Energy Physics
Condensed Matter Physics

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10.1016/j.jmr.2005.06.006

Cite this

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title = "Selecting ordered environments in NMR of spin 3/2 nuclei via frequency-sweep pulses",

abstract = "We demonstrate that frequency-swept pulses can be used for the selective and enhanced detection of quadrupolar nuclei located in anisotropic environments. The primary driving force for this technique development is the field of sodium-MRI, where sodium signals from locally ordered environments are known to be diagnostic of cartilage defects. We demonstrate here simple one-dimensional images of model systems, in which the signals from free sodium ions are suppressed, while ordered sodium is detected via the narrow central transition signal.",

keywords = "Contrast mechanism, Double-frequency sweep, Double-quantum filter, Quadrupolar coupling, Satellite transitions, Sodium MRI",

author = "Wen Ling and Alexej Jerschow",

note = "Funding Information: We acknowledge funds from the NYU Whitehead Fellowship for Junior Faculty in the Biological and Biomedical Sciences. NYU{\textquoteright}s NMR facilities were supported by a NSF Grant MRI-0116222. We acknowledge support by Dr. Chin Lin and the Molecular Imaging and Contrast Agent Working Group at NYU, as well as, stimulating discussions with Dr. Gil Navon, Dr. Uzi Eliav, and Dr. Philip W. Kuchel.",

year = "2005",

month = oct,

doi = "10.1016/j.jmr.2005.06.006",

language = "English (US)",

volume = "176",

pages = "234--238",

journal = "Journal of Magnetic Resonance",

issn = "1090-7807",

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T1 - Selecting ordered environments in NMR of spin 3/2 nuclei via frequency-sweep pulses

AU - Ling, Wen

AU - Jerschow, Alexej

N1 - Funding Information: We acknowledge funds from the NYU Whitehead Fellowship for Junior Faculty in the Biological and Biomedical Sciences. NYU’s NMR facilities were supported by a NSF Grant MRI-0116222. We acknowledge support by Dr. Chin Lin and the Molecular Imaging and Contrast Agent Working Group at NYU, as well as, stimulating discussions with Dr. Gil Navon, Dr. Uzi Eliav, and Dr. Philip W. Kuchel.

PY - 2005/10

Y1 - 2005/10

N2 - We demonstrate that frequency-swept pulses can be used for the selective and enhanced detection of quadrupolar nuclei located in anisotropic environments. The primary driving force for this technique development is the field of sodium-MRI, where sodium signals from locally ordered environments are known to be diagnostic of cartilage defects. We demonstrate here simple one-dimensional images of model systems, in which the signals from free sodium ions are suppressed, while ordered sodium is detected via the narrow central transition signal.

AB - We demonstrate that frequency-swept pulses can be used for the selective and enhanced detection of quadrupolar nuclei located in anisotropic environments. The primary driving force for this technique development is the field of sodium-MRI, where sodium signals from locally ordered environments are known to be diagnostic of cartilage defects. We demonstrate here simple one-dimensional images of model systems, in which the signals from free sodium ions are suppressed, while ordered sodium is detected via the narrow central transition signal.

KW - Contrast mechanism

KW - Double-frequency sweep

KW - Double-quantum filter

KW - Quadrupolar coupling

KW - Satellite transitions

KW - Sodium MRI

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VL - 176

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JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

IS - 2

ER -

Selecting ordered environments in NMR of spin 3/2 nuclei via frequency-sweep pulses

Abstract

Keywords

ASJC Scopus subject areas

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