@article{d7caca615d4d47ab9c64484cb87bebe7,
title = "Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation",
abstract = "This work demonstrates a self-assembling peptide strategy to form finite, molecularly defined trigonal bipyramidal-like hexamers which offer control over multivalent ligand display for enhanced tumor targeting.",
keywords = "Amino Acid Sequence, Biological Transport, Cell Line, Tumor, Collagen/chemistry, Humans, Ligands, Molecular Dynamics Simulation, Nanofibers/chemistry, Optical Imaging, Peptides/chemistry, Protein Conformation, Protein Multimerization, Receptors, Cell Surface/metabolism",
author = "Xiushuang Yuan and Linhai Jiang and Weike Chen and Bo Song and Wei Chen and Xiaobing Zuo and Xiankai Sun and Xiaopeng Li and Kent Kirshenbaum and Shizhong Luo and He Dong",
note = "Funding Information: We acknowledge the University of Texas at Arlington and the National Science Foundation (CHE-1507946 to K. Kirshenbaum) to provide financial support for the project. Beijing University of Chemical Technology provided fellowship for X. Yuan. We thank Dr Chad Brautigam and Shih-Chia Tso for the technical support and discussions on the AUC data analysis. This work was supported in part through the NYU IT High Performance Computing resources, services and staff expertise. The SAXS measurements were performed at Beamline 12-ID-B of the Advanced Photon Source, a U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2020",
month = jul,
day = "4",
doi = "10.1039/d0cc02066d",
language = "English (US)",
volume = "56",
pages = "7128--7131",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "52",
}