Selfassembly of metallic nanoparticle arrays by DNA scaffolding

Shoujun Xiao; Furong Liu; Abbey E. Rosen; James F. Hainfeld; Nadrian C. Seeman; Karin Musier-Forsyth; Richard A. Kiehl

doi:10.1023/A:1021145208328

Selfassembly of metallic nanoparticle arrays by DNA scaffolding

Shoujun Xiao, Furong Liu, Abbey E. Rosen, James F. Hainfeld, Nadrian C. Seeman, Karin Musier-Forsyth, Richard A. Kiehl

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaf-folding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.

Original language	English (US)
Pages (from-to)	313-317
Number of pages	5
Journal	Journal of Nanoparticle Research
Volume	4
Issue number	4
DOIs	https://doi.org/10.1023/A:1021145208328
State	Published - 2002

Keywords

DNA
Nanoelectronics
Nanoparticles
Nanotechnology
Self-assembly

ASJC Scopus subject areas

General Chemistry
Condensed Matter Physics
Bioengineering
Atomic and Molecular Physics, and Optics
General Materials Science
Modeling and Simulation

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10.1023/A:1021145208328

Cite this

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title = "Selfassembly of metallic nanoparticle arrays by DNA scaffolding",

abstract = "We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaf-folding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.",

keywords = "DNA, Nanoelectronics, Nanoparticles, Nanotechnology, Self-assembly",

author = "Shoujun Xiao and Furong Liu and Rosen, {Abbey E.} and Hainfeld, {James F.} and Seeman, {Nadrian C.} and Karin Musier-Forsyth and Kiehl, {Richard A.}",

note = "Funding Information: We would like to acknowledge D.L. Anderson and C.M. Peterson for discussions regarding TEM imaging of DNA samples. This work was primarily supported by the National Science Foundation (Exploratory Research in Biosystems at the Nanoscale). Additional support to N.C.S. was provided by NIGMS, ONR, NSF and DARPA. The STEM imaging was performed at the Brookhaven National Laboratory, supported by NIH and the DOE.",

year = "2002",

doi = "10.1023/A:1021145208328",

language = "English (US)",

volume = "4",

pages = "313--317",

journal = "Journal of Nanoparticle Research",

issn = "1388-0764",

publisher = "Springer Netherlands",

number = "4",

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TY - JOUR

T1 - Selfassembly of metallic nanoparticle arrays by DNA scaffolding

AU - Xiao, Shoujun

AU - Liu, Furong

AU - Rosen, Abbey E.

AU - Hainfeld, James F.

AU - Seeman, Nadrian C.

AU - Musier-Forsyth, Karin

AU - Kiehl, Richard A.

N1 - Funding Information: We would like to acknowledge D.L. Anderson and C.M. Peterson for discussions regarding TEM imaging of DNA samples. This work was primarily supported by the National Science Foundation (Exploratory Research in Biosystems at the Nanoscale). Additional support to N.C.S. was provided by NIGMS, ONR, NSF and DARPA. The STEM imaging was performed at the Brookhaven National Laboratory, supported by NIH and the DOE.

PY - 2002

Y1 - 2002

N2 - We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaf-folding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.

AB - We report the self-assembly of metallic nanoparticle arrays using DNA crystals as a programmable molecular scaf-folding. Gold nanoparticles, 1.4 nm in diameter, are assembled in two-dimensional arrays with interparticle spacings of 4 and 64 nm. The nanoparticles form precisely integrated components, which are covalently bonded to the DNA scaffolding. These results show that heterologous chemical systems can be assembled into precise, programmable geometrical arrangements by DNA scaffolding, thereby representing a critical step toward the realization of DNA nanotechnology.

KW - DNA

KW - Nanoelectronics

KW - Nanoparticles

KW - Nanotechnology

KW - Self-assembly

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DO - 10.1023/A:1021145208328

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SN - 1388-0764

VL - 4

SP - 313

EP - 317

JO - Journal of Nanoparticle Research

JF - Journal of Nanoparticle Research

IS - 4

ER -

Selfassembly of metallic nanoparticle arrays by DNA scaffolding

Abstract

Keywords

ASJC Scopus subject areas

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