TY - JOUR
T1 - Semiautomated roi analysis in dynamic mr studies. Part i
T2 - Image analysis tools for automatic correction of organ displacements
AU - Gerig, Guido
AU - Kikinis, Ron
AU - Kuoni, Walter
AU - Von Schulthess, Gustav K.
AU - Kübler, Olaf
PY - 1991/9
Y1 - 1991/9
N2 - The most important problem in the analysis of time sequences is the compensation for artifactual motion. Owing to motion, medical images of the abdominal region do not represent organs with fixed configuration. Analysis of organ function with dynamic contrast medium studies using regions of interest (ROIs) is thus not readily accomplished. Images of the organ of interest need to be registered and corrected prior to a detailed local analysis. We have developed an image analysis scheme that allows the automatic detection of the organ contours, the extraction of the motion parameters per frame, and the registration of images. The complete procedure requires only minimal user interaction and results in a readjusted image sequence, where organs of interest remain fixed. Both a visual analysis of the dynamic behavior of functional properties and a quantitative statistical analysis of signal intensity versus time within local ROIs are considerably facilitated using the corrected series.
AB - The most important problem in the analysis of time sequences is the compensation for artifactual motion. Owing to motion, medical images of the abdominal region do not represent organs with fixed configuration. Analysis of organ function with dynamic contrast medium studies using regions of interest (ROIs) is thus not readily accomplished. Images of the organ of interest need to be registered and corrected prior to a detailed local analysis. We have developed an image analysis scheme that allows the automatic detection of the organ contours, the extraction of the motion parameters per frame, and the registration of images. The complete procedure requires only minimal user interaction and results in a readjusted image sequence, where organs of interest remain fixed. Both a visual analysis of the dynamic behavior of functional properties and a quantitative statistical analysis of signal intensity versus time within local ROIs are considerably facilitated using the corrected series.
KW - Artifacts
KW - Image quality
KW - Magnetic resonance imaging, Localization
KW - Magnetic resonance imaging, Techniques
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U2 - 10.1097/00004728-199109000-00001
DO - 10.1097/00004728-199109000-00001
M3 - Article
C2 - 1885789
AN - SCOPUS:0025939073
VL - 15
SP - 725
EP - 732
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
SN - 0363-8715
IS - 5
ER -