Sensitivity analysis for frequency-domain optical tomography of small tissue volumes

Xuejun Gu, Uwe J. Netz, Kui Ren, Jürgen Beuthan, Andreas H. Hielscher

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We perform numerical and experimental sensitivity analyses for the imaging problem in small-volume optical tomography with the frequency-domain equation of radiative transfer as light propagation model. Varying the optical properties, tissue geometries, and contrast, we show that source modulation frequencies in the range of 300-600MHz yield maximal signal-to-noise ratios and therefore maximal sensitivity to tissue inhomogeneities.

    Original languageEnglish (US)
    Title of host publicationBiomedical Topical Meeting, BIO 2006
    PublisherOptical Society of America
    ISBN (Print)1557528071, 9781557528070
    StatePublished - 2006
    EventBiomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States
    Duration: Mar 19 2006Mar 19 2006

    Publication series

    NameOptics InfoBase Conference Papers
    ISSN (Electronic)2162-2701

    Conference

    ConferenceBiomedical Topical Meeting, BIO 2006
    CountryUnited States
    CityFort Lauderdale, FL
    Period3/19/063/19/06

    ASJC Scopus subject areas

    • Instrumentation
    • Atomic and Molecular Physics, and Optics

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