Serum and salivary cardiac analytes in acute myocardial infarction related to oral health status

Jeffrey L. Ebersole, Richard J. Kryscio, Charles Campbell, Denis F. Kinane, John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Craig S. Miller

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

With the advent of an increased emphasis on the potential to utilize biomarkers in saliva for systemic diseases, the issue of existing oral disease is an important consideration that could adversely affect the interpretation of diagnostic results obtained from saliva. We addressed the question does a patient's oral inflammation status confound biomarker levels used in diagnosis of acute myocardial infarction (AMI). The results demonstrated that multiple serum biomarkers and a few salivary biomarkers reflected the cardiac event. Importantly, oral health of the individual had minimal impact on the validity of the serum or salivary biomarker effectiveness.

Original languageEnglish (US)
Title of host publicationSensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV
PublisherSPIE
ISBN (Print)9781628410495
DOIs
StatePublished - 2014
EventSensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV - Baltimore, MD, United States
Duration: May 5 2014May 7 2014

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9112
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Other

OtherSensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV
CountryUnited States
CityBaltimore, MD
Period5/5/145/7/14

Keywords

  • Acute myocardial infarction
  • cardiac biomarkers
  • inflammation
  • oral health
  • saliva

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Ebersole, J. L., Kryscio, R. J., Campbell, C., Kinane, D. F., McDevitt, J. T., Christodoulides, N., Floriano, P. N., & Miller, C. S. (2014). Serum and salivary cardiac analytes in acute myocardial infarction related to oral health status. In Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV [91120G] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 9112). SPIE. https://doi.org/10.1117/12.2058734