Short- vs Long-Course Antibiotics for Acute Exacerbations of Chronic Bronchitis

Raffi A. Bashlian; Carolyn J. Sun; Caroline G. Dorsen

doi:10.1016/j.nurpra.2012.01.001

Short- vs Long-Course Antibiotics for Acute Exacerbations of Chronic Bronchitis

Raffi A. Bashlian, Carolyn J. Sun, Caroline G. Dorsen

Nursing

Research output: Contribution to journal › Article › peer-review

Abstract

The increasing prevalence of acute exacerbations of chronic bronchitis (AECB) is a significant public health problem, costing the United States health care system over $1.9 billion in 2008. While AECB is mainly treated with antibiotics, the ideal duration of antibacterial treatment remains unclear. Antibiotic overprescription, growing prevalence of bacterial resistance to antibiotics worldwide, and difficulties with patient adherence are ongoing issues. The purpose of this literature review is to identify the most effective duration of antibiotic therapy administration (short- vs long-course antibiotic therapy) for patients with AECB, synthesizing the findings for clinical application.

Original language	English (US)
Pages (from-to)	534-539
Number of pages	6
Journal	Journal for Nurse Practitioners
Volume	8
Issue number	7
DOIs	https://doi.org/10.1016/j.nurpra.2012.01.001
State	Published - Jul 2012

Keywords

AECB
Adult
Drug therapy
Review of literature
Short course
Treatment outcome

ASJC Scopus subject areas

Advanced and Specialized Nursing

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10.1016/j.nurpra.2012.01.001

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abstract = "The increasing prevalence of acute exacerbations of chronic bronchitis (AECB) is a significant public health problem, costing the United States health care system over $1.9 billion in 2008. While AECB is mainly treated with antibiotics, the ideal duration of antibacterial treatment remains unclear. Antibiotic overprescription, growing prevalence of bacterial resistance to antibiotics worldwide, and difficulties with patient adherence are ongoing issues. The purpose of this literature review is to identify the most effective duration of antibiotic therapy administration (short- vs long-course antibiotic therapy) for patients with AECB, synthesizing the findings for clinical application.",

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AB - The increasing prevalence of acute exacerbations of chronic bronchitis (AECB) is a significant public health problem, costing the United States health care system over $1.9 billion in 2008. While AECB is mainly treated with antibiotics, the ideal duration of antibacterial treatment remains unclear. Antibiotic overprescription, growing prevalence of bacterial resistance to antibiotics worldwide, and difficulties with patient adherence are ongoing issues. The purpose of this literature review is to identify the most effective duration of antibiotic therapy administration (short- vs long-course antibiotic therapy) for patients with AECB, synthesizing the findings for clinical application.

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KW - Drug therapy

KW - Review of literature

KW - Short course

KW - Treatment outcome

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Short- vs Long-Course Antibiotics for Acute Exacerbations of Chronic Bronchitis

Abstract

Keywords

ASJC Scopus subject areas

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