Simulating the fluid dynamics of natural and prosthetic heart valves using the immersed boundary method

Boyce E. Griffith, Xiaoyu Luo, David M. McQueen, Charles S. Peskin

Research output: Contribution to journalArticlepeer-review

Abstract

The immersed boundary method is both a general mathematical framework and a particular numerical approach to problems of fluid-structure interaction. In the present work, we describe the application of the immersed boundary method to the simulation of the fluid dynamics of heart valves, including a model of a natural aortic valve and a model of a chorded prosthetic mitral valve. Each valve is mounted in a semi-rigid flow chamber. In the case of the mitral valve, the flow chamber is a circular pipe, and in the case of the aortic valve, the flow chamber is a model of the aortic root. The model valves and flow chambers are immersed in a viscous incompressible fluid, and realistic fluid boundary conditions are prescribed at the upstream and downstream ends of the chambers. To connect the immersed boundary models to the boundaries of the fluid domain, we introduce a novel modification of the standard immersed boundary scheme. In particular, near the outer boundaries of the fluid domain, we modify the construction of the regularized delta function which mediates fluid-structure coupling in the immersed boundary method, whereas in the interior of the fluid domain, we employ a standard four-point delta function which is frequently used with the immersed boundary method. The standard delta function is used wherever possible, and the modified delta function continuously transitions to the standard delta function away from the outer boundaries of the fluid domain. Three-dimensional computational results are presented to demonstrate the capabilities of our immersed boundary approach to simulating the fluid dynamics of heart valves.

Original languageEnglish (US)
Pages (from-to)137-177
Number of pages41
JournalInternational Journal of Applied Mechanics
Volume1
Issue number1
DOIs
StatePublished - Mar 2009

Keywords

  • Immersed boundary method
  • adaptive mesh refinement
  • aortic valve
  • fluid-structure interaction
  • mitral valve
  • physical boundary conditions
  • prosthetic valve

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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