Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions

Ashley N. Powers; Rahul Satija

doi:10.1186/s13059-015-0778-y

Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions

Ashley N. Powers, Rahul Satija

Biology and Genomics

Research output: Contribution to journal › Article › peer-review

Abstract

Cell-cycle fluctuations drive significant transcriptomic heterogeneity in murine hematopoietic stem cells. Additionally, deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice.

Original language	English (US)
Article number	199
Journal	Genome biology
Volume	16
Issue number	1
DOIs	https://doi.org/10.1186/s13059-015-0778-y
State	Published - Sep 21 2015

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/s13059-015-0778-y

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title = "Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions",

abstract = "Cell-cycle fluctuations drive significant transcriptomic heterogeneity in murine hematopoietic stem cells. Additionally, deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice.",

author = "Powers, {Ashley N.} and Rahul Satija",

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AU - Satija, Rahul

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Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions

Abstract

ASJC Scopus subject areas

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