Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions

Ashley N. Powers, Rahul Satija

Research output: Contribution to journalArticlepeer-review

Abstract

Cell-cycle fluctuations drive significant transcriptomic heterogeneity in murine hematopoietic stem cells. Additionally, deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice.

Original languageEnglish (US)
Article number199
JournalGenome biology
Volume16
Issue number1
DOIs
StatePublished - Sep 21 2015

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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