Sleep disorders, glucose regulation, and type 2 diabetes

Leslie Faith Morritt Taub, Nancy S. Redeker

Research output: Contribution to journalArticle

Abstract

Recent epidemiological, biological, and behavioral evidence suggests that sleep disorders may contribute to the development of diabetes; conversely, diabetes itself may contribute to sleep disorders. Sleep appears to moderate the neurohormones that regulate blood glucose. Sleep deprivation and sleep disorders contribute to pathophysiological changes associated with the development of type 2 diabetes. In people who already have diabetes, sleep deprivation contributes to elevations of hemoglobin A1c. Symptoms that occur as a result of diabetes, such as nocturia and neuropathic pain, may in turn contribute to sleep disturbance and exacerbate sleep deprivation. The purposes of this article are to examine the scientific basis for the associations between diabetes and sleep, identify gaps in the understanding of the empirical underpinnings of these relationships, and propose directions for future research.

Original languageEnglish (US)
Pages (from-to)231-243
Number of pages13
JournalBiological Research for Nursing
Volume9
Issue number3
DOIs
StatePublished - Jan 2008

Keywords

  • Circadian rhythm
  • Diabetes
  • Inflammatory markers
  • Insulin resistance
  • Sleep
  • Sleep apnea

ASJC Scopus subject areas

  • Research and Theory

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