Sodium MRI: Methods and applications

Guillaume Madelin; Jae Seung Lee; Ravinder R. Regatte; Alexej Jerschow

doi:10.1016/j.pnmrs.2014.02.001

Sodium MRI: Methods and applications

Guillaume Madelin, Jae Seung Lee, Ravinder R. Regatte, Alexej Jerschow

Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

Sodium NMR spectroscopy and MRI have become popular in recent years through the increased availability of high-field MRI scanners, advanced scanner hardware and improved methodology. Sodium MRI is being evaluated for stroke and tumor detection, for breast cancer studies, and for the assessment of osteoarthritis and muscle and kidney functions, to name just a few. In this article, we aim to present an up-to-date review of the theoretical background, the methodology, the challenges, limitations, and current and potential new applications of sodium MRI.

Original language	English (US)
Pages (from-to)	14-47
Number of pages	34
Journal	Progress in Nuclear Magnetic Resonance Spectroscopy
Volume	79
DOIs	https://doi.org/10.1016/j.pnmrs.2014.02.001
State	Published - May 2014

Keywords

In vivo MRI
Quadrupolar coupling
Relaxation
Sodium MRI
Spherical tensors

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Nuclear and High Energy Physics
Spectroscopy

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10.1016/j.pnmrs.2014.02.001

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@article{59acfaf969324f97aa51504cf4c79c48,

title = "Sodium MRI: Methods and applications",

abstract = "Sodium NMR spectroscopy and MRI have become popular in recent years through the increased availability of high-field MRI scanners, advanced scanner hardware and improved methodology. Sodium MRI is being evaluated for stroke and tumor detection, for breast cancer studies, and for the assessment of osteoarthritis and muscle and kidney functions, to name just a few. In this article, we aim to present an up-to-date review of the theoretical background, the methodology, the challenges, limitations, and current and potential new applications of sodium MRI.",

keywords = "In vivo MRI, Quadrupolar coupling, Relaxation, Sodium MRI, Spherical tensors",

author = "Guillaume Madelin and Lee, {Jae Seung} and Regatte, {Ravinder R.} and Alexej Jerschow",

note = "Funding Information: A.J. acknowledges funding from National Science Foundation CHE 0957586 , and NIH/NIBIB/NIAMS 1 R01 EB016045-01 . R.R.R. acknowledges funding from National Institutes of Health , 1R01AR053133 , 1R01AR056260 , and 1R01AR060238 , and J.S.L. acknowledges funding from National Institutes of Health K25AR060269 . We thank Dr. Uzi Eliav, Dr. Philip Kuchel, Dr. Ivan Maximov, Dr. Charles S. Springer Jr., and Dr. Keith Thulborn for commenting on our manuscript and providing helpful suggestions. ",

year = "2014",

month = may,

doi = "10.1016/j.pnmrs.2014.02.001",

language = "English (US)",

volume = "79",

pages = "14--47",

journal = "Progress in Nuclear Magnetic Resonance Spectroscopy",

issn = "0079-6565",

publisher = "Elsevier",

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TY - JOUR

T1 - Sodium MRI

T2 - Methods and applications

AU - Madelin, Guillaume

AU - Lee, Jae Seung

AU - Regatte, Ravinder R.

AU - Jerschow, Alexej

N1 - Funding Information: A.J. acknowledges funding from National Science Foundation CHE 0957586 , and NIH/NIBIB/NIAMS 1 R01 EB016045-01 . R.R.R. acknowledges funding from National Institutes of Health , 1R01AR053133 , 1R01AR056260 , and 1R01AR060238 , and J.S.L. acknowledges funding from National Institutes of Health K25AR060269 . We thank Dr. Uzi Eliav, Dr. Philip Kuchel, Dr. Ivan Maximov, Dr. Charles S. Springer Jr., and Dr. Keith Thulborn for commenting on our manuscript and providing helpful suggestions.

PY - 2014/5

Y1 - 2014/5

N2 - Sodium NMR spectroscopy and MRI have become popular in recent years through the increased availability of high-field MRI scanners, advanced scanner hardware and improved methodology. Sodium MRI is being evaluated for stroke and tumor detection, for breast cancer studies, and for the assessment of osteoarthritis and muscle and kidney functions, to name just a few. In this article, we aim to present an up-to-date review of the theoretical background, the methodology, the challenges, limitations, and current and potential new applications of sodium MRI.

AB - Sodium NMR spectroscopy and MRI have become popular in recent years through the increased availability of high-field MRI scanners, advanced scanner hardware and improved methodology. Sodium MRI is being evaluated for stroke and tumor detection, for breast cancer studies, and for the assessment of osteoarthritis and muscle and kidney functions, to name just a few. In this article, we aim to present an up-to-date review of the theoretical background, the methodology, the challenges, limitations, and current and potential new applications of sodium MRI.

KW - In vivo MRI

KW - Quadrupolar coupling

KW - Relaxation

KW - Sodium MRI

KW - Spherical tensors

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U2 - 10.1016/j.pnmrs.2014.02.001

DO - 10.1016/j.pnmrs.2014.02.001

M3 - Review article

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SN - 0079-6565

VL - 79

SP - 14

EP - 47

JO - Progress in Nuclear Magnetic Resonance Spectroscopy

JF - Progress in Nuclear Magnetic Resonance Spectroscopy

ER -

Sodium MRI: Methods and applications

Abstract

Keywords

ASJC Scopus subject areas

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