Sodium MRI: Methods and applications

Guillaume Madelin, Jae Seung Lee, Ravinder R. Regatte, Alexej Jerschow

Research output: Contribution to journalReview articlepeer-review


Sodium NMR spectroscopy and MRI have become popular in recent years through the increased availability of high-field MRI scanners, advanced scanner hardware and improved methodology. Sodium MRI is being evaluated for stroke and tumor detection, for breast cancer studies, and for the assessment of osteoarthritis and muscle and kidney functions, to name just a few. In this article, we aim to present an up-to-date review of the theoretical background, the methodology, the challenges, limitations, and current and potential new applications of sodium MRI.

Original languageEnglish (US)
Pages (from-to)14-47
Number of pages34
JournalProgress in Nuclear Magnetic Resonance Spectroscopy
StatePublished - May 2014


  • In vivo MRI
  • Quadrupolar coupling
  • Relaxation
  • Sodium MRI
  • Spherical tensors

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Nuclear and High Energy Physics
  • Spectroscopy


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