TY - GEN
T1 - Soft computing control of Type 1 diabetes described at molecular levels
AU - Kovács, L.
AU - György, A.
AU - Benyó, B.
AU - Benyó, Z.
AU - Kovács, A.
PY - 2009
Y1 - 2009
N2 - The blood glucose system is one of the most important systems of the human body, since energy transport is fulfilled through this complex endocrine control process. Because of its great importance (in case of failure, its primary consequence diabetes mellitus appears), many models were published, most of them with phenomenological approach. The current paper focuses on a new molecular model published recently [1]. By modifying it to model the failure of pancreatic insulin secretion that characterizes Type 1 diabetes mellitus, soft computing based controller is designed. Rough rule base is generated with subtractive clustering which is followed by its refinement by parameter tuning. As a result, an Adaptive Neuro-Fuzzy Inference System (ANFIS) is created. Simulation results are in accordance with the behavior of the healthy human blood glucose system.
AB - The blood glucose system is one of the most important systems of the human body, since energy transport is fulfilled through this complex endocrine control process. Because of its great importance (in case of failure, its primary consequence diabetes mellitus appears), many models were published, most of them with phenomenological approach. The current paper focuses on a new molecular model published recently [1]. By modifying it to model the failure of pancreatic insulin secretion that characterizes Type 1 diabetes mellitus, soft computing based controller is designed. Rough rule base is generated with subtractive clustering which is followed by its refinement by parameter tuning. As a result, an Adaptive Neuro-Fuzzy Inference System (ANFIS) is created. Simulation results are in accordance with the behavior of the healthy human blood glucose system.
UR - http://www.scopus.com/inward/record.url?scp=70350214461&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70350214461&partnerID=8YFLogxK
U2 - 10.1109/SACI.2009.5136220
DO - 10.1109/SACI.2009.5136220
M3 - Conference contribution
AN - SCOPUS:70350214461
SN - 9781424444786
T3 - Proceedings - 2009 5th International Symposium on Applied Computational Intelligence and Informatics, SACI 2009
SP - 99
EP - 104
BT - Proceedings - 2009 5th International Symposium on Applied Computational Intelligence and Informatics, SACI 2009
T2 - 2009 5th International Symposium on Applied Computational Intelligence and Informatics, SACI 2009
Y2 - 28 May 2009 through 29 May 2009
ER -