Spectral domain optical coherence tomography for detection of foveal morphology in patients with nystagmus

Tara H. Cronin, Richard W. Hertle, Hiroshi Ishikawa, Joel S. Schuman

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Purpose: To evaluate the feasibility of spectral domain optical coherence tomography (SD-OCT) macular scanning as a means of studying the afferent visual system in nystagmus patients. Methods: Nystagmus patients who underwent SD-OCT, clinical evaluation, and eye movement recordings were recruited for this prospective, single-center, noncomparative study. Three SD-OCT macular three-dimensional cube scans per eye (200 × 200 × 1024 samplings in a 6 × 6 mm region) were obtained for qualitative retinal morphology analysis. Results: Nineteen patients (6-68 years; average, 19 years) were analyzed. Of these, 17 patients had infantile nystagmus syndrome, and 2 had fusion maldevelopment nystagmus; 17 patients (89%) had associated sensory system abnormalities, including 9 (47%) with albinism. Macular images were successfully obtained in all but 1 patient (95%). Of the 8 successfully imaged oculocutaneous patients, 7 patients demonstrated "fovea plana," and all demonstrated abnormal morphology. Conclusion: SD-OCT reliably provides detailed structural imaging of the fovea in nystagmus patients.{A figure is presented}{A figure is presented}.

    Original languageEnglish (US)
    Pages (from-to)563-566
    Number of pages4
    JournalJournal of AAPOS
    Volume13
    Issue number6
    DOIs
    StatePublished - Dec 2009

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Ophthalmology

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