Stereoselective total syntheses of herbicidin C and aureonuclemycin through late-stage glycosylation

Dominik Hager, Peter Mayer, Christian Paulitz, Jörg Tiebes, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

Better late than never! Two herbicidins, members of an important family of nucleoside antibiotics, have been synthesized for the first time. The route integrates a stereoselective C-glycosylation with several reagent-controlled stereoselective transformations and a surprisingly facile and highly diastereoselective late-stage N-glycosylation.

Original languageEnglish (US)
Pages (from-to)6525-6528
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number26
DOIs
StatePublished - Jun 25 2012

Keywords

  • antibiotics
  • glycosylation
  • nucleosides
  • stereoselective synthesis
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint Dive into the research topics of 'Stereoselective total syntheses of herbicidin C and aureonuclemycin through late-stage glycosylation'. Together they form a unique fingerprint.

  • Cite this