@article{62b7becdb4ba4386a9ca0b9fc68deada,
title = "Strategies used in the detection of Acute/early HIV infections. The NIMH multisite acute HIV infection study: I",
abstract = "Acute/early HIV infection plays a critical role in onward HIV transmission. Detection of HIV infections during this period provides an important early opportunity to offer interventions which may prevent further transmission. In six US cities, persons with acute/early HIV infection were identified using either HIV RNA testing of pooled sera from persons screened HIV antibody negative or through clinical referral of persons with acute or early infections. Fifty-one cases were identified and 34 (68%) were enrolled into the study; 28 (82%) were acute infections and 6 (18%) were early infections. Of those enrolled, 13 (38%) were identified through HIV pooled testing of 7,633 HIV antibody negative sera and 21 (62%) through referral. Both strategies identified cases that would have been missed under current HIV testing and counseling protocols. Efforts to identify newly infected persons should target specific populations and geographic areas based on knowledge of the local epidemiology of incident infections.",
keywords = "Acute HIV infection, Early detection of acute HIV infection, HIV RNA testing, Nucleic acid amplification tests",
author = "Kerndt, {Peter R.} and Robert Dubrow and Getahun Aynalem and Mayer, {Kenneth H.} and Curt Beckwith and Remien, {Robert H.} and Truong, {Hong Ha M.} and Apurva Uniyal and Michael Chien and Brooks, {Ronald A.} and Vigil, {Ofilio R.} and Steward, {Wayne T.} and Michael Merson and Rotheram-Borus, {Mary Jane} and Morin, {Stephen F.}",
note = "Funding Information: Primary Funding for this study was provided by the National Institute of Mental Health as supplements to the following AIDS Research Centers: P30MH062246, Center for AIDS Prevention Studies, University of California San Francisco, PI: Stephen F. Morin, PhD (Study Coordinating Center) P30MH043520, HIV Center for Clinical and Behavioral Research, New York State Psychiatric Institute and Columbia University, PI: Anke A. Ehrhardt, PhD (Qualitative Data Analysis Center) P30MH062512, HIV Neurobehavioral Research Center, University of California San Diego, PI: Igor Grant, MD (Mental Health Assessment Center) P30MH052776, Center for AIDS Intervention Research, Medical College of Wisconsin, PI: Jeffrey A. Kelly, PhD P30MH058107, Center for HIV Identification, Prevention and Treatment Services, University of California Los Angeles; PI: Mary Jane Rotheram-Borus, PhD. P30MH062294, Center for Interdisciplinary Research on AIDS, Yale University, PI: Michael H. Merson, MD Additional funding was provided by: P30AI42853, Lifespan/Tufts/Brown Center for AIDS Research; PI: Charles C.J. Carpenter, MD AI43638, Acute Infection and Early Disease Research Program, University of California San Diego, PI: Susan Little, MD. Steering Committee (Lead Scientists)",
year = "2009",
month = dec,
doi = "10.1007/s10461-009-9580-8",
language = "English (US)",
volume = "13",
pages = "1037--1045",
journal = "AIDS and Behavior",
issn = "1090-7165",
publisher = "Springer New York",
number = "6",
}