Strengthening Neuroplasticity in Substance Use Recovery Through Lifestyle Intervention

Steven G. Sugden, Gia Merlo, Sam Manger

Research output: Contribution to journalReview articlepeer-review


The incidence of substance use and behavioral addictions continues to increase throughout the world. The Global Burden of Disease Study shows a growing impact in disability-adjusted life years due to substance use. Substance use impacts families, communities, health care, and legal systems; yet, the vast majority of individuals with substance use disorders do not seek treatment. Within the United States, new legislation has attempted to increase the availability of buprenorphine, but the impact of substance use continues. Although medications and group support therapy have been the mainstay of treatment for substance use, lifestyle medicine offers a valuable adjunct therapy that may help strengthen substance use recovery through healthy neuroplastic changes.

Original languageEnglish (US)
JournalAmerican Journal of Lifestyle Medicine
StateAccepted/In press - 2024


  • dopamine reward pathway
  • lifestyle interventions
  • neuroinflammation
  • pillars of lifestyle medicine
  • serotonin
  • substance use disorders

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Health Policy
  • Public Health, Environmental and Occupational Health


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