Structural basis of Hox specificity

David S. Wilson, Claude Desplan

Research output: Contribution to journalArticlepeer-review

Abstract

On their own, the homeotic selector (Hox) transcriptional regulators bind very short, rather similar DNA sequences. To elevate their functional specificity, Hox proteins heterodimerize with other homeodomain-containing proteins. The structural basis for this fruitful partnership is now coming into view.

Original languageEnglish (US)
Pages (from-to)297-300
Number of pages4
JournalNature Structural Biology
Volume6
Issue number4
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry
  • Genetics

Fingerprint Dive into the research topics of 'Structural basis of Hox specificity'. Together they form a unique fingerprint.

Cite this