Structural basis of Hox specificity

David S. Wilson; Claude Desplan

doi:10.1038/7524

Structural basis of Hox specificity

Research output: Contribution to journal › Article › peer-review

Abstract

On their own, the homeotic selector (Hox) transcriptional regulators bind very short, rather similar DNA sequences. To elevate their functional specificity, Hox proteins heterodimerize with other homeodomain-containing proteins. The structural basis for this fruitful partnership is now coming into view.

Original language	English (US)
Pages (from-to)	297-300
Number of pages	4
Journal	Nature Structural Biology
Volume	6
Issue number	4
DOIs	https://doi.org/10.1038/7524
State	Published - 1999

ASJC Scopus subject areas

Structural Biology
Biochemistry
Genetics

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10.1038/7524

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Structural basis of Hox specificity

Abstract

ASJC Scopus subject areas

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