Structural characterization of genuine (-)-pipermethystine, (-)-epoxypipermethystine, (+)-dihydromethysticin and yangonin from the kava plant (Piper methysticum)

Panče Naumov, Klaus Dragull, Masahiro Yoshioka, Chung Shih Tang, Seik Weng Ng

Research output: Contribution to journalArticle


Two alkaloids, (-)-pipermethystine and (-)-epoxypipermethystine, and two lactones, (+)-dihydromethysticin and yangonin, were isolated from the kava plant (Piper methysticum) and crystallographically authenticated.

Original languageEnglish (US)
Pages (from-to)1333-1336
Number of pages4
JournalNatural Product Communications
Issue number8
StatePublished - Dec 1 2008



  • Dihydromethysticin
  • Epoxypipermethystine
  • Kava alkaloids
  • Kava plant
  • Kavalactones
  • Pipermethystine
  • Yangonin

ASJC Scopus subject areas

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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