Abstract
Zanamivir, the active ingredient of the antiviral drug Relenza, is the most potent of the four currently approved neuraminidase inhibitors for treatment of pandemic strains of influenza. A combination of solution creeping and vapor diffusion of antisolvent was successfully applied to obtain two crystalline polymorphic dihydrates and to accomplish the first structure determination of zanamivir with X-ray diffraction.
Original language | English (US) |
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Pages (from-to) | 770-774 |
Number of pages | 5 |
Journal | Crystal Growth and Design |
Volume | 14 |
Issue number | 2 |
DOIs | |
State | Published - Feb 5 2014 |
ASJC Scopus subject areas
- General Chemistry
- General Materials Science
- Condensed Matter Physics