Studies toward the biomimetic total synthesis of (-)-PF-1018

Robert Webster, Boris Gaspar, Peter Mayer, Dirk Trauner

Research output: Contribution to journalArticlepeer-review


Pericyclic reaction cascades are unparalleled in their ability to quickly generate complex structures with excellent stereocontrol. Herein, the use of a biomimetic Stille/8π electrocyclization/Diels-Alder cascade to successfully assemble the core structure of (-)-PF-1018 is reported.

Original languageEnglish (US)
Pages (from-to)1866-1869
Number of pages4
JournalOrganic Letters
Issue number8
StatePublished - Apr 19 2013

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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