Substance Use Patterns of HIV-Infected Russian Women with and Without Hepatitis C Virus Co-infection

Jennifer L. Brown, Ralph J. DiClemente, Jessica M. Sales, Eve S. Rose, Polina Safonova, Olga S. Levina, Nikolay Belyakov, Vadim V. Rassokhin

Research output: Contribution to journalArticlepeer-review


Individuals with HIV and hepatitis C virus (HCV) co-infection may experience substance use related health complications. This study characterized substance use patterns between HIV/HCV co-infected and HIV mono-infected Russian women. HIV-infected women (N = 247; M age = 30.0) in St. Petersburg, Russia, completed a survey assessing substance use, problematic substance use, and the co-occurrence of substance use and sexual behaviors. Covariate adjusted logistic and linear regression analyses indicated that HIV/HCV co-infected participants (57.1 %) reported more lifetime drug use (e.g., heroin: AOR: 13.2, 95 % CI 4.9, 35.3, p < .001), problem drinking (β = 1.2, p = .05), substance use problems (β = 1.3, p = .009), and increased likelihood of past injection drug use (AOR: 26.4, 95 % CI 8.5, 81.9, p < .001) relative to HIV mono-infected individuals. HIV/HCV co-infection was prevalent and associated with increased substance use and problematic drug use. Findings highlight the need for ongoing substance use and HIV/HCV risk behavior assessment and treatment among HIV/HCV co-infected Russian women.

Original languageEnglish (US)
Pages (from-to)2398-2407
Number of pages10
JournalAIDS and Behavior
Issue number10
StatePublished - Oct 1 2016


  • HCV
  • HIV-infected
  • Problematic substance use
  • Russian women
  • Substance use

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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