Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB

Biochemistry, Genetics and Molecular Biology

• Protein Biosynthesis 100%
• Small Molecule 100%
• Nerve Cell Differentiation 50%
• Induced Pluripotent Stem Cell 50%
• Cell Growth 50%
• C-Terminus 50%
• Complex Formation 50%
• Ternary Complex 50%
• Cell Death 50%
• Initiation Factor 50%
• Eukaryotic Translation 50%
• Guanine Nucleotide Exchange Factor 50%
• Intellectual Disability 50%
• Guanosine Triphosphate 50%

Keyphrases

• ISRIB 100%
• MEHMO Syndrome 100%
• EIF2S3 33%
• X-linked Intellectual Disability 16%
• Translation Initiation Factor eIF2 16%
• CD123 16%
• Eukaryotic Translation Initiation Factor 16%