Surface characterization and in vivo evaluation of dual acid-etched and grit-blasted/acid-etched implants in sheep

Daniel Yoo, Charles Marin, Gileade Freitas, Nick Tovar, Estevam A. Bonfante, Hellen S. Teixeira, Malvin N. Janal, Paulo G. Coelho

Research output: Contribution to journalArticle


Purpose: Dual acid-etching is widely used to modify dental implant topography and enhance early bone healing. This study evaluated the histomorphometric, biomechanical, and histological bone response to acid-etched (AA) in comparison with grit-blasted/acid-etched (GB) and machined control (C) implants within sites of relatively low-bone remodeling rates. Materials and Methods: Implant surface topography was evaluated by scanning electron microscopy and optical interferometry (IFM). Six adult male sheep (n 6) received 72 Ti-6Al-4V implants (n 24 per surface) in both ilium (n 12 per bone bilaterally). The implants remained for 3 and 6 weeks in vivo. The histomorphometric parameters bone-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated. Biomechanical analysis consisted of torque-to-interface failure. Results: IFM analysis showed the highest average surface roughness for GB and the highest density of summits and developed surface area percentage (P < 0.01) for AA. No difference was observed in BAFO for all groups in 3 and 6 weeks. Increased BIC and torque resistance were observed for AA implants at both time points after implantation. Conclusions: Overall, improved bone-to-implant response was observed for the AA implant surface.

Original languageEnglish (US)
Pages (from-to)256-262
Number of pages7
JournalImplant dentistry
Issue number3
StatePublished - Jun 4 2015



  • biomechanical
  • dental implants
  • osseointegration
  • surface

ASJC Scopus subject areas

  • Oral Surgery

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