Switching Gears: Translational Mastery of Transcription during Memory Formation

Charles A. Hoeffer, Eric Klann

Research output: Contribution to journalShort survey

Abstract

A critical molecular requirement underlying many forms of long-lasting synaptic plasticity and memory is the de novo synthesis of mRNAs and proteins. In a recent paper in Cell, Costa-Mattioli et al. present data from a pharmacogenetic study that places a key regulatory event in the "neural decision" to undergo these persistent neuronal changes under translational control mediated by eIF2α.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalNeuron
Volume54
Issue number2
DOIs
StatePublished - Apr 19 2007

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Switching Gears: Translational Mastery of Transcription during Memory Formation'. Together they form a unique fingerprint.

  • Cite this