Symptom management of HIV-related diarrhea by using normal foods: A randomized controlled clinical trial

Joyce K. Anastasi, Bernadette Capili, Gee Kim, Don McMahon, Margaret M. Heitkemper

Research output: Contribution to journalArticle

Abstract

The purpose of this randomized clinical trial was to determine the efficacy of a dietary intervention to reduce the frequency of bowel movements and improve stool consistency as compared with subjects assigned to a control group. The study enrolled HIV patients with a history of three or more episodes of diarrhea for 3 weeks or more. Seventy-five subjects were enrolled, of which 38 were randomized to the treatment group and 37 to the control group. Six study sessions were scheduled over a 24-week period. At 24 weeks, the stool frequency reduced 28% in the treatment group and 15% in the control group (F = 9.22, p < .001) and stool consistency improved 20% in the treatment group and 8% in the control group (F = 9.98, p < .001). The results showed that the intervention was effective in reducing stool frequency and improving stool consistency in HIV patients with chronic diarrhea for up to 6 months of treatment.

Original languageEnglish (US)
Pages (from-to)47-57
Number of pages11
JournalJournal of the Association of Nurses in AIDS Care
Volume17
Issue number2
DOIs
StatePublished - 2006

Keywords

  • Clinical trial
  • Diarrhea
  • HIV
  • Nutrition intervention
  • Symptom management

ASJC Scopus subject areas

  • Advanced and Specialized Nursing

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